Description

(2-(Trifluoromethoxy)Phenyl)Acrylic Acid is a specialized fluorinated acrylic acid derivative, serving as a high-value building block in advanced organic synthesis. This compound matters for its unique molecular structure, which combines a phenylacrylic acid core with a trifluoromethoxy substituent, imparting desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: A potential intermediate for creating fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorination chemistry and C-C bond formation reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	(2-(Trifluoromethoxy)Phenyl)Acrylic Acid
CAS No.	399580-48-4
Molecular Formula	C10H7F3O3
Molecular Weight	232.16 g/mol
Synonyms	2-(Trifluoromethoxy)cinnamic acid; 3-[2-(Trifluoromethoxy)phenyl]prop-2-enoic acid; (2-Trifluoromethoxyphenyl)acrylic acid; α,β-Unsaturated carboxylic acid with trifluoromethoxy substituent; 2-(Trifluoromethoxy)benzeneacrylic acid; (2-TFMP)Acrylic Acid; (o-Trifluoromethoxyphenyl)acrylic acid
EINECS	Contact for details

Quality Control

Every batch of (2-(Trifluoromethoxy)Phenyl)Acrylic Acid undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and cGMP manufacturing environments. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.