Description

Tarafenacin is a high-purity, non-peptide small molecule compound with significant pharmacological activity. It serves as a potent and selective antagonist for the M3 muscarinic acetylcholine receptor, making it a critical intermediate in advanced pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical industry focused on developing novel therapeutics for urological disorders, such as overactive bladder (OAB).

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting muscarinic receptors.
• Drug Discovery & Development: Utilized in preclinical research for studying M3 receptor antagonism and its therapeutic effects.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Used in vitro studies to investigate signal transduction pathways mediated by acetylcholine.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Tarafenacin
CAS No.	385367-47-5
Molecular Formula	C₂₆H₃₀N₂O₃
Molecular Weight	418.53 g/mol
Synonyms	YM905; Tarafenacin (YM-905); (3R)-1-[2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl]-3-(diphenylacetyl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one; 1-[2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl]-3-[(2,2-diphenylacetyl)amino]-4,5-dihydro-1H-imidazol-2-one; (R)-YM-905
EINECS	Contact for details

Quality Control

Our Tarafenacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm
Assay	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.