Description

3-Chloro-4-Fluoro-5-(Trifluoromethyl)Benzoic Acid is a high-purity, multi-functional aromatic carboxylic acid building block, distinguished by its unique halogen and trifluoromethyl substitution pattern. This compound is critical for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of specific steric and electronic properties into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into polymer chains to impart specific properties such as increased chemical resistance, altered solubility, or enhanced thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterification, and amide bond formation to construct complex molecular architectures in academic and industrial research.
• Chemical Research & Development: A valuable reference standard and reagent for method development and exploratory chemistry in fine chemical laboratories.

Basic Information

Product Name	3-Chloro-4-Fluoro-5-(Trifluoromethyl)Benzoic Acid
CAS No.	381229-48-7
Molecular Formula	C8H3ClF4O2
Molecular Weight	242.56 g/mol
Synonyms	3-Chloro-4-fluoro-5-(trifluoromethyl)benzoic acid; 5-(Trifluoromethyl)-3-chloro-4-fluorobenzoic acid; Benzoic acid, 3-chloro-4-fluoro-5-(trifluoromethyl)-; 3-Chloro-4-fluoro-alpha,alpha,α-trifluoro-m-toluic acid; 381229-48-7; 3-Cl-4-F-5-CF3-Benzoic Acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-5-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.