Description

3-(2-Amino-3-Fluorophenyl)Benzoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and amino group offer critical modifications to biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine moiety enhances efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as fluorinated polymers and semiconductors.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated aromatic scaffolds.

Basic Information

Product Name	3-(2-Amino-3-Fluorophenyl)Benzoic Acid
CAS No.	376592-45-9
Molecular Formula	C13H10FNO2
Molecular Weight	231.22 g/mol
Synonyms	[2-Amino-6-(carboxyphenyl)]-3-fluorobenzene; 3-Fluoro-2-aminobiphenyl-4'-carboxylic Acid; 2'-Amino-3'-fluorobiphenyl-4-carboxylic Acid; 3'-Fluoro-2'-aminobiphenyl-4-carboxylic Acid; Benzoic acid, 3-(2-amino-3-fluorophenyl)-; 4-Carboxy-3'-fluoro-2'-aminobiphenyl; 3-(2-Amino-3-fluorophenyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-(2-Amino-3-Fluorophenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.