Description

2-Fluoro-4-(6-Methoxypyridin-3-Yl)Benzoic Acid is a high-value fluorinated aromatic building block that combines a benzoic acid core with a methoxypyridine moiety. This compound is critical for pharmaceutical research and development, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorine and heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorinated aromatic structure can enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Advanced Material Development: A starting material for creating specialty polymers or organic electronic materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	2-Fluoro-4-(6-Methoxypyridin-3-Yl)Benzoic Acid
CAS No.	370864-61-2
Molecular Formula	C13H10FNO3
Molecular Weight	247.22 g/mol
Synonyms	2-Fluoro-4-(6-methoxy-3-pyridinyl)benzoic acid; 4-(6-Methoxy-3-pyridinyl)-2-fluorobenzoic acid; 2-Fluoro-4-(6-methoxypyridin-3-yl)benzoic acid; 370864-61-2; Benzoic acid, 2-fluoro-4-(6-methoxy-3-pyridinyl)-; 2-Fluoro-4-(6-methoxy-pyridin-3-yl)-benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(6-Methoxypyridin-3-Yl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support custom purity grades to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.