Description

Benzoic Acid, 4-[[(4-Chloro-5,6,7,8-Tetrahydro-3-Hydroxy-5,5,8,8-Tetramethyl-2-Naphthalenyl)Carbonyl]Amino]-2,6-Difluoro- is a high-purity, complex aromatic carboxylic acid derivative designed for advanced research and development applications. This compound is valued for its specific molecular architecture, which incorporates halogen and hydroxyl functional groups, making it a critical building block in synthetic chemistry. It is primarily sought by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, leveraging its difluoro and chlorinated naphthalene structure.
• Chemical Biology Probe: Acts as a specialized ligand or inhibitor in biochemical assays to study enzyme function and receptor interactions.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique thermal or optical properties.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in organic synthesis and medicinal chemistry.
• Custom Synthesis Building Block: Provided to fine chemical manufacturers for the production of bespoke compounds under contract.

Basic Information

Product Name	Benzoic Acid, 4-[[(4-Chloro-5,6,7,8-Tetrahydro-3-Hydroxy-5,5,8,8-Tetramethyl-2-Naphthalenyl)Carbonyl]Amino]-2,6-Difluoro-
CAS No.	367273-07-2
Molecular Formula	C24H24ClF2NO4
Molecular Weight	463.90 g/mol
Synonyms	4-[[(4-Chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetramethyl-2-naphthoyl)amino]-2,6-difluorobenzoic acid; 2,6-Difluoro-4-[[(4-chloro-5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]benzoic acid; AGN 194204; AGN-194204; RAR agonist; Retinoic Acid Receptor Agonist; Synthetic retinoid intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent GMP-like guidelines to ensure batch-to-batch consistency and traceability. Every lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR/LC-MS for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.