Description

5-[3-(Trifluoromethoxy)Phenyl]-2-Furoic Acid is a high-value fluorinated organic building block with the CAS registry number 355818-02-9. This compound is prized for its unique structural motif combining a furoic acid core with a trifluoromethoxy-substituted aromatic ring, which is critical for modulating the physicochemical properties of advanced molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its trifluoromethoxy group can enhance metabolic stability, lipophilicity, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Active Ingredient Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group contributes to improved biological activity and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Incorporated into specialty polymers to impart specific characteristics such as chemical resistance, thermal stability, or unique optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel fluorinated compounds and reaction pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services for client-specific molecules.

Basic Information

Product Name	5-[3-(Trifluoromethoxy)Phenyl]-2-Furoic Acid
CAS No.	355818-02-9
Molecular Formula	C₁₂H₇F₃O₄
Molecular Weight	272.18 g/mol
Synonyms	5-[3-(Trifluoromethoxy)phenyl]-2-furancarboxylic acid; 2-Furoic acid, 5-[3-(trifluoromethoxy)phenyl]-; 5-(3-Trifluoromethoxyphenyl)furan-2-carboxylic acid; 3-Trifluoromethoxyphenyl-2-furoic acid; α-Furoic acid, 5-[m-(trifluoromethoxy)phenyl]-; 5-(3-(Trifluoromethoxy)phenyl)furan-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-[3-(Trifluoromethoxy)Phenyl]-2-Furoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.