Description

Ethyl 2,3,4-Trifluorobenzoate is a high-purity fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzoate ring, which significantly influences the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials where fluorination is a key design strategy.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl benzoate moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated compounds used in electronic display technologies, contributing to improved performance and stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and esterification/transesterification processes to introduce the 2,3,4-trifluorophenyl group.
• Polymer Modification: Used to incorporate fluorine into polymer chains, enhancing properties like chemical resistance, thermal stability, and weatherability.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and creating compound libraries for screening.

Basic Information

Product Name	Ethyl 2,3,4-Trifluorobenzoate
CAS No.	351354-50-2
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	Benzoic acid, 2,3,4-trifluoro-, ethyl ester; Ethyl 2,3,4-trifluorobenzoate; 2,3,4-Trifluorobenzoic Acid Ethyl Ester; Ethyl 2,3,4-Trifluorobenzenecarboxylate; Ethyl α,β,γ-Trifluorobenzoate; E2,3,4TFB; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ethyl 2,3,4-Trifluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.