Description

Ethyl 4-Fluoro-3-Hydroxybenzoate is a high-purity fluorinated benzoate ester derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic combination of a phenolic hydroxyl group and a fluorine atom on the aromatic ring, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules in drug discovery and active ingredient development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-inflammatory, and anti-infective applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Polymer & Specialty Chemical Modifier: Incorporated to introduce fluorine and phenolic functionality into polymers, enhancing properties like chemical resistance, surface energy, and thermal stability.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new fluorination chemistry, esterification reactions, and heterocyclic compound synthesis.

Basic Information

Product Name	Ethyl 4-Fluoro-3-Hydroxybenzoate
CAS No.	351317-28-7
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	4-Fluoro-3-hydroxybenzoic acid ethyl ester; Ethyl 4-fluoro-3-hydroxybenzoate; Benzoic acid, 4-fluoro-3-hydroxy-, ethyl ester; 3-Hydroxy-4-fluorobenzoic acid ethyl ester; Ethyl 3-hydroxy-4-fluorobenzoate; 351317-28-7; 4-Fluoro-3-hydroxy-benzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-3-Hydroxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.