Description

3',5'-Difluoro-Biphenyl-4-Carboxylic Acid is a high-purity fluorinated biphenyl derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates fluorine atoms at strategic positions to modulate the electronic and steric properties of target compounds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a core component in the production of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to influence dielectric anisotropy and thermal stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transport material or a host material in the emissive layer of OLED devices, enhancing efficiency and color purity.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with improved chemical resistance, thermal stability, and low surface energy for coatings and engineering plastics.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and the discovery of new functional molecules.

Basic Information

Product Name	3',5'-Difluoro-Biphenyl-4-Carboxylic Acid
CAS No.	350682-84-7
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	4-(3,5-Difluorophenyl)benzoic Acid; [1,1'-Biphenyl]-4-carboxylic acid, 3',5'-difluoro-; 3,5-Difluoro-4'-carboxybiphenyl; 3',5'-Difluoro-4-biphenylcarboxylic Acid; Biphenyl-4-carboxylic acid, 3',5'-difluoro-; 3,5-Difluorobiphenyl-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 3',5'-Difluoro-Biphenyl-4-Carboxylic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets a typical purity specification of ≥98% (HPLC), with custom purities up to ≥99.5% available. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.