Description

n-tert-Butyl-3-(trifluoromethyl)benzamide is a specialized benzamide derivative characterized by a tert-butyl amide group and a trifluoromethyl substituent on the aromatic ring. This compound is a valuable pharmaceutical intermediate and organic building block, prized for its ability to impart metabolic stability and modulate lipophilicity in active molecules. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, or insecticides, where the trifluoromethyl group enhances biological activity.
• Organic Synthesis Reagent: Used in academic and industrial laboratories for constructing complex organic molecules, leveraging the tert-butyl amide as a protective group or directing moiety.
• Material Science Research: Potential precursor for specialty polymers or advanced materials where fluorine-containing aromatic units are required.
• Chemical Reference Standard: Employed as a high-purity standard in analytical testing and quality control processes within chemical manufacturing.

Basic Information

Product Name	n-tert-Butyl-3-(Trifluoromethyl)Benzamide
CAS No.	340136-34-7
Molecular Formula	C12H14F3NO
Molecular Weight	245.24 g/mol
Synonyms	3-(Trifluoromethyl)-N-(1,1-dimethylethyl)benzamide; N-tert-Butyl-3-(trifluoromethyl)benzamide; N-(tert-Butyl)-3-(trifluoromethyl)benzamide; Benzamide, N-(1,1-dimethylethyl)-3-(trifluoromethyl)-; 3-Trifluoromethyl-N-tert-butylbenzamide; N-(tert-Butyl)-alpha,alpha,α-trifluoro-m-toluamide; m-(Trifluoromethyl)-N-tert-butylbenzamide
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-3-(trifluoromethyl)benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.