Description

Ethyl 4-Fluoro-2-Methylbenzoylformate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. This compound serves as a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is essential for research chemists and process development scientists working on novel active ingredients, where its specific substitution pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated organic molecules for electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects and scale-up services for clients in fine chemicals.
• Academic and R&D Laboratories: Used in methodological research and the discovery of new synthetic routes involving fluorinated compounds.

Basic Information

Product Name	Ethyl 4-Fluoro-2-Methylbenzoylformate
CAS No.	334477-07-5
Molecular Formula	C₁₂H₁₃FO₃
Molecular Weight	224.23 g/mol
Synonyms	Ethyl (4-Fluoro-2-methylphenyl)(oxo)acetate; 4-Fluoro-2-methylbenzoylformic Acid Ethyl Ester; Ethyl 4-Fluoro-2-methyl-α-oxobenzeneacetate; α-Oxo-4-fluoro-2-methylbenzeneacetic Acid Ethyl Ester; 2-Methyl-4-fluorobenzoylformic Acid Ethyl Ester; Ethyl 2-Methyl-4-fluorobenzoylformate; (4-Fluoro-2-methylphenyl)glyoxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-2-Methylbenzoylformate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.