Description

3,5-Difluoro-2-Nitrobenzoic Acid is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and nitro groups on the benzoic acid scaffold, which allows for precise structural modifications to develop novel compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by manufacturers of specialty dyes and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where fluorine substitution enhances biological activity and stability.
• Liquid Crystal & OLED Material Development: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Specialty Dye & Pigment Manufacturing: Employed to introduce fluorine and nitro functional groups into dye molecules, altering their color fastness and spectral properties.
• Cross-Coupling Reactions: The carboxylic acid and halogen substituents make it a suitable substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for creating custom compound libraries.

Basic Information

Product Name	3,5-Difluoro-2-Nitrobenzoic Acid
CAS No.	331765-71-0
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	2-Nitro-3,5-difluorobenzoic Acid; 3,5-Difluoro-2-nitrobenzoic acid; Benzoic acid, 3,5-difluoro-2-nitro-; 331765-71-0; 3,5-Difluoro-2-nitro-benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-2-Nitrobenzoic Acid is produced and tested under a strict quality management system. We ensure high purity and consistent performance through advanced analytical techniques including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.