Description

Methyl 3-Chloro-5-Fluorobenzoate is a high-purity fluorinated aromatic ester, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials, where the introduction of halogenated aromatic motifs is required.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the chloro-fluoro substitution pattern.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Building block for polymers and small molecules used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D labs.
• Custom Synthesis: Starting material for the contract manufacturing of complex, tailor-made fine chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	Methyl 3-Chloro-5-Fluorobenzoate
CAS No.	327056-75-7
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	3-Chloro-5-fluorobenzoic acid methyl ester; Methyl 3-chloro-5-fluorobenzoate; Benzoic acid, 3-chloro-5-fluoro-, methyl ester; 3-Chloro-5-fluorobenzoic acid methyl ester; Methyl 3-chloro-5-fluorobenzoate; 327056-75-7; Methyl m-chloro-p-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-5-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for reliable integration into your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.