Description

4-[4-(4-Fluorophenyl)-1,3-Thiazol-2-Yl]Benzenecarboxylic Acid is a high-value heterocyclic aromatic carboxylic acid building block, critical for advanced organic synthesis. Its molecular architecture, featuring a fluorinated phenyl-thiazole core, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to incorporate sophisticated fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Development: Used to create novel fungicides and herbicides where the fluorinated thiazole moiety enhances biological activity and stability.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers requiring specific electronic properties.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic systems and as a ligand precursor in catalysis.
• Fluorine Chemistry Studies: A valuable compound for investigating structure-activity relationships (SAR) in molecules containing fluorine atoms.

Basic Information

Product Name	4-[4-(4-Fluorophenyl)-1,3-Thiazol-2-Yl]Benzenecarboxylic Acid
CAS No.	321429-96-3
Molecular Formula	C16H10FNO2S
Molecular Weight	299.32 g/mol
Synonyms	2-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]benzoic acid; 4-(4-(4-Fluorophenyl)thiazol-2-yl)benzoic acid; 4-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]benzoic acid; 4-(4-(p-Fluorophenyl)thiazol-2-yl)benzoic acid; 4-(2-(4-Fluorophenyl)thiazol-4-yl)benzoic acid (isomer); 321429-96-3; FPTBA; 4-Carboxy-4'-(4-fluorophenyl)-2,2'-bithiazole (related structure)
EINECS	Contact for details

Quality Control

Our production of 4-[4-(4-Fluorophenyl)-1,3-Thiazol-2-Yl]Benzenecarboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with customer specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.5% / ≥ 99.0% (High Purity Grades)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.