Description

2'-Deoxyguanosine 5'-Monophosphate is a high-purity nucleotide monophosphate essential for life science research and pharmaceutical development. This compound serves as a critical building block for oligonucleotide synthesis and is fundamental in studying DNA replication, repair mechanisms, and enzymatic processes. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in molecular biology, diagnostics, and therapeutic agent development.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of DNA and RNA sequences.
• Biochemical Research: Used as a substrate for enzymes like kinases and polymerases to study nucleic acid metabolism and signaling pathways.
• Diagnostic Reagent Manufacturing: Incorporated into probes and primers for PCR, qPCR, and other molecular diagnostic assays.
• Pharmaceutical Intermediates: Serves as a starting material or intermediate in the development of nucleotide-based antiviral or anticancer therapeutics.
• Cell Culture & Media Supplements: Utilized in specialized cell culture media to support the growth of fastidious cell lines.
• Reference Standard: Acts as a high-purity analytical standard for quality control in pharmaceutical and diagnostic manufacturing.

Basic Information

Product Name	2'-Deoxyguanosine 5'-Monophosphate
CAS No.	312693-67-7
Molecular Formula	C10H14N5O7P
Molecular Weight	347.22 g/mol
Synonyms	dGMP; Deoxyguanylic Acid; 2'-Deoxy-GMP; 5'-dGMP; Deoxyguanosine Monophosphate; Guanosine 5'-(dihydrogen phosphate) 2'-deoxy-; 2'-Deoxyguanosine 5'-(dihydrogen phosphate)
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine 5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for residual solvents and endotoxins where applicable. We provide Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation. For extended storage under inert atmosphere, consult the technical data sheet.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines
Bacterial Endotoxins (LAL)	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.