Description

trans-2 5-Bis(Trifluoromethyl)Cinnamic is a high-value fluorinated cinnamic acid derivative characterized by its unique trifluoromethyl-substituted aromatic structure. This compound is prized for its role as a sophisticated building block in advanced organic synthesis, where its fluorine atoms impart desirable properties like enhanced lipophilicity and metabolic stability to target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated motifs for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl groups can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated organic electronic materials, contributing to the performance of displays and lighting technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create specialty polymers with unique thermal, chemical, or surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reactions, catalytic processes, and material science applications.

Basic Information

Product Name	trans-2 5-Bis(Trifluoromethyl)Cinnamic
CAS No.	312619-48-0
Molecular Formula	C₁₂H₆F₆O₂
Molecular Weight	296.17 g/mol
Synonyms	(E)-3-[2,5-Bis(trifluoromethyl)phenyl]acrylic acid; 3-(2,5-Bis(trifluoromethyl)phenyl)-2-propenoic acid; trans-3-(2,5-Bis(trifluoromethyl)phenyl)acrylic acid; 2,5-Bis(trifluoromethyl)cinnamic acid; (E)-3-(2,5-Bis(trifluoromethyl)phenyl)prop-2-enoic acid; α,2,5-Bis(trifluoromethyl)cinnamic acid
EINECS	Contact for details

Quality Control

Our trans-2 5-Bis(Trifluoromethyl)Cinnamic is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production applications. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.