Description

2-(3,4-Difluorophenyl)-2-Methylpropanoic Acid is a high-purity fluorinated organic acid building block of significant commercial and research interest. Its value lies in its unique structure, which incorporates a gem-dimethyl substituted propanoic acid moiety on a difluorinated aromatic ring, making it a versatile intermediate for advanced synthesis. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for creating advanced herbicides, fungicides, and pesticides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of fluorinated organic compounds for electronic applications, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a monomer or functionalization agent for introducing fluorinated aromatic units into polymers to alter thermal stability, chemical resistance, and surface properties.
• Chemical Research & Development: A valuable building block in academic and industrial labs for exploring new fluorination chemistry, asymmetric synthesis, and structure-activity relationship (SAR) studies.
• Advanced Material Science: Employed in the development of specialty coatings, adhesives, and engineered materials that benefit from the incorporation of fluorine atoms.

Basic Information

Product Name	2-(3,4-Difluorophenyl)-2-Methylpropanoic Acid
CAS No.	306761-55-7
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2-(3,4-Difluorophenyl)-2-methylpropionic acid; α,α-Dimethyl-3,4-difluorobenzenepropanoic acid; 3,4-Difluoro-α,α-dimethylbenzenepropanoic acid; 2-Methyl-2-(3,4-difluorophenyl)propanoic acid; 2-(3,4-Difluorophenyl)-2-methylpropanoate (anion form); 306761-55-7 (CAS); DFMPA
EINECS	Contact for details

Quality Control

Our production of 2-(3,4-Difluorophenyl)-2-Methylpropanoic Acid adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific regulatory or internal quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under dry conditions to prevent moisture absorption, which can affect purity and stability. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.