Description

Deoxy-(Thymidylyl-Adenylyl-Thymidylyl-Adenylic Acid) is a defined-sequence oligonucleotide, specifically a tetramer composed of deoxythymidylyl and deoxyadenylyl units. This compound is a critical building block and research tool in molecular biology and nucleic acid chemistry, valued for its precise structure and high purity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications such as primer synthesis, probe development, and the study of DNA structure and function.

Application

• Primer Synthesis: Serves as a short, defined-sequence primer for PCR, DNA sequencing, and other enzymatic amplification techniques.
• Probe Development: Used as a core component in the design and synthesis of labeled probes for hybridization assays and diagnostic tests.
• Oligonucleotide Assembly: Acts as a key intermediate or building block in the solid-phase synthesis of longer DNA strands.
• Biochemical Research: Employed in fundamental studies of DNA-protein interactions, nucleic acid structure, and enzyme kinetics.
• Antisense & Therapeutic Research: Investigated as a component in the development of antisense oligonucleotides and other nucleic acid-based therapeutics.
• Quality Control Standard: Functions as a reference standard for analytical methods like HPLC and mass spectrometry within quality control laboratories.

Basic Information

Product Name	Deoxy-(Thymidylyl-Adenylyl-Thymidylyl-Adenylic Acid)
CAS No.	39726-35-7
Molecular Formula	C39H48N15O23P3
Molecular Weight	1187.80 g/mol
Synonyms	d(TATA); T-A-T-A Tetramer; Thymidylyl(3'→5')adenylyl(3'→5')thymidylyl(3'→5')adenylic Acid; Deoxythymidylyl-deoxyadenylyl-deoxythymidylyl-deoxyadenylic Acid; Oligonucleotide d(TATA); DNA Tetramer d(TATA); 5'-d(TpTpApTpA)-3'; 5'-Thymidylyl-thymidylyl-adenylyl-thymidylyl-adenylic Acid-3'
EINECS	Contact for details

Quality Control

Our Deoxy-(Thymidylyl-Adenylyl-Thymidylyl-Adenylic Acid) is manufactured under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, UV spectroscopy, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular weight
Purity (HPLC)	≥ 95% (Area % at 260 nm)
Assay (UV)	≥ 85% (on dried basis)
Water Content (KF)	≤ 5.0%
Extinction Coefficient (ε260)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.