Description

Viomycin Sulfate is a sulfate salt form of the tuberactinomycin antibiotic viomycin, primarily recognized for its potent antimycobacterial activity. This compound is a critical reference standard and active pharmaceutical ingredient (API) in research and development targeting drug-resistant tuberculosis. It is essential for pharmaceutical manufacturers, clinical research organizations, and analytical laboratories engaged in antimicrobial drug development, quality control, and microbiological studies.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in HPLC, LC-MS, and microbiological assays for quality control and method validation.
• Antimicrobial Research: Serves as a key tool compound in studying mechanisms of action against *Mycobacterium tuberculosis*, including multi-drug resistant (MDR) and extensively drug-resistant (XDR) strains.
• In-vitro Diagnostic Reagents: Incorporated into culture media and sensitivity tests for the identification and susceptibility profiling of mycobacterial infections.
• Biochemical Research: Utilized in studies of bacterial protein synthesis inhibition, specifically targeting the 30S ribosomal subunit and inducing translational misreading.
• API Intermediate: Employed in the synthesis and formulation development of specialized anti-tuberculosis medications and combination therapies.

Basic Information

Product Name	Viomycin Sulfate
CAS No.	37883-00-4
Molecular Formula	C25H43N13O10 · xH2SO4
Molecular Weight	685.71 g/mol (for base, excluding sulfate)
Synonyms	Viomycin Sulphate; Tuberactinomycin B; Vinactin A; Viocin; Florimycin Sulfate; Viomycin Monosulfate; Antibiotic VM 1; Delphicort
EINECS	Contact for details

Quality Control

Our Viomycin Sulfate is manufactured and tested under strict quality management systems. Each batch is subjected to comprehensive analytical testing including identity confirmation, purity assay, and impurity profiling to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (1% solution)	4.5 - 6.5
Specific Rotation	-30° to -40° (c=1 in H2O)
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets Ph. Eur. 2.6.12/2.6.13 criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.