Description

Ristocetin A CAS NO 37361-31-2 is a glycopeptide antibiotic complex isolated from *Amycolatopsis orientalis* (formerly *Nocardia orientalis*). This compound is of significant value in biochemical and pharmaceutical research due to its unique mechanism of action, which involves binding to the D-alanyl-D-alanine terminus of peptidoglycan precursors, inhibiting bacterial cell wall synthesis. It is primarily utilized by research institutions, diagnostic laboratories, and pharmaceutical developers engaged in antimicrobial studies, coagulation research, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a critical tool for studying bacterial cell wall biosynthesis and the mechanisms of glycopeptide antibiotics.
• Coagulation Studies: Employed in platelet aggregation assays and the study of von Willebrand factor (vWF) interactions, serving as a diagnostic reagent for certain platelet function disorders.
• Antimicrobial Susceptibility Testing: Acts as a reference standard for evaluating bacterial resistance to glycopeptide antibiotics, particularly in research settings.
• Pharmaceutical Development: Serves as a starting material or reference compound in the research and development of new antibacterial agents.
• Quality Control: Used as a certified reference material (CRM) in the quality assurance and standardization of related pharmaceutical products and diagnostic kits.

Basic Information

Product Name	Ristocetin A
CAS No.	37361-31-2
Molecular Formula	C95H103N7O32Cl2
Molecular Weight	2067.8 g/mol
Synonyms	Ristomycin A; Ristocetin A sulfate; Antibiotic A 3823 complex; Ristocetin sulfate; Spontin; Ristocetin component A; Ristocetin A (sulfate); Ristocetin sulfate complex
EINECS	253-488-9

Quality Control

Our Ristocetin A is produced and tested under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and identification data. We adhere to relevant guidelines for reference standards, ensuring product integrity for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0 %
pH (1% solution)	4.0 - 6.0
Specific Rotation	Contact for details
Biological Potency	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.