Description

5-(Chlorosulphonyl)-2-Fluorobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both a reactive chlorosulphonyl group and a carboxylic acid moiety, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing sulfonamide or benzoic acid derivatives.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its fluorinated aromatic core.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex fluorinated dyes and high-performance pigments.
• Ligand and Catalyst Development: Utilized in academic and industrial research to create novel ligands for metal catalysis and organocatalysts.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-(Chlorosulphonyl)-2-Fluorobenzoic Acid
CAS No.	37098-75-2
Molecular Formula	C7H4ClFO4S
Molecular Weight	238.62 g/mol
Synonyms	2-Fluoro-5-(chlorosulfonyl)benzoic Acid; 5-Chlorosulfonyl-2-fluorobenzoic Acid; Benzoic acid, 2-fluoro-5-(chlorosulfonyl)-; 2-Fluorobenzoic-5-sulfonyl chloride; 5-(Chlorosulfonyl)-2-fluorobenzoic acid; 37098-75-2; 2-Fluoro-5-chlorosulfonylbenzoic acid
EINECS	Contact for details

Quality Control

Our 5-(Chlorosulphonyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.