Description

Benzoic Acid (Trifluoromethanesulfonic Acid) Anhydride is a highly reactive acylating agent and a key trifluoromethanesulfonyl (triflyl) source. This compound is critical for introducing the powerful electron-withdrawing triflyl group into target molecules, significantly altering their electronic properties and reactivity. It is an essential intermediate for researchers and manufacturers in advanced organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty materials where enhanced stability or specific reactivity is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the trifluoromethanesulfonyl moiety to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, fungicides, and insecticides with tailored properties.
• Polymer & Material Science: Employed in the production of specialty polymers, resins, and advanced materials requiring specific acid or electron-accepting functionalities.
• Catalyst & Ligand Preparation: Used to synthesize novel organometallic catalysts and ligands for asymmetric synthesis and other catalytic processes.
• Organic Synthesis Reagent: Acts as a versatile reagent for acylation and sulfonylation reactions in complex multi-step synthetic routes.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	Benzoic Acid (Trifluoromethanesulfonic Acid) Anhydride
CAS No.	36967-85-8
Molecular Formula	C8H5F3O4S
Molecular Weight	254.18 g/mol
Synonyms	Benzoic Triflic Anhydride; Benzoic Acid Triflate Anhydride; Benzoyl Trifluoromethanesulfonate; Benzoyl Triflate; Trifluoromethanesulfonic Acid Benzoic Anhydride; N-Benzoyltriflimide; (Benzoyloxy)(trifluoromethyl)sulfonyl]methanone
EINECS	Contact for details

Quality Control

Our Benzoic Acid (Trifluoromethanesulfonic Acid) Anhydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from incompatible materials such as bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.