Description

Lergotrile CAS NO 36945-03-6 is a synthetic ergot alkaloid derivative with significant pharmacological interest. This compound is valued for its dopaminergic activity and serves as a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents targeting neurological and endocrine disorders.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced dopaminergic agents and other specialized pharmaceuticals.
• Neurological Research: Used in preclinical studies to investigate mechanisms related to dopamine receptors and potential treatments for Parkinson's disease.
• Endocrine Research: Employed in studies exploring prolactin secretion inhibition and related hormonal pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Chemical Synthesis: Utilized in organic synthesis for the preparation of more complex ergoline-based molecules.

Basic Information

Item	Detail
Product Name	Lergotrile
CAS No.	36945-03-6
Molecular Formula	C₁₇H₁₈ClN₃O
Molecular Weight	315.80 g/mol
Synonyms	2-Chloro-6-methyl-8β-ergolineacetonitrile; Lergotrile mesylate; 2-Chloro-6-methylergoline-8β-acetonitrile; 8β-(2-Chloro-1-cyanoethyl)-6-methylergoline; Lergotril; (8β)-2-Chloro-6-methylergoline-8-acetonitrile
EINECS	Contact for details

Quality Control

Our Lergotrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.