Description

Methyl Pentafluorobenzoate is a high-purity fluorinated aromatic ester, a key building block in advanced organic synthesis. Its value lies in the unique reactivity and stability imparted by the pentafluorophenyl group, enabling precise chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require reliable, high-quality intermediates for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface properties, increase chemical resistance, or modify dielectric constants.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Derivatization Agent: Employed in analytical chemistry for the derivatization of compounds to enhance detection in GC-MS or HPLC analysis.
• Ligand & Catalyst Preparation: Used to synthesize fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & R&D: A valuable reagent for methodological development and exploratory research in fluoroorganic chemistry.

Basic Information

Product Name	Methyl Pentafluorobenzoate
CAS No.	36629-42-2
Molecular Formula	C8H3F5O2
Molecular Weight	226.10 g/mol
Synonyms	Methyl 2,3,4,5,6-Pentafluorobenzoate; Pentafluorobenzoic Acid Methyl Ester; Methyl Perfluorobenzoate; Methyl Pentafluorobenzenecarboxylate; Methyl α,α,α,2,3,4,5,6-Octafluorotoluate (deprecated); Methyl Pentafluorophenylcarboxylate; Methyl Pentafluorobenzene-1-carboxylate; MFB (abbreviation)
EINECS	Contact for details

Quality Control

Our Methyl Pentafluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.