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3-Furylmethylpenicillin CAS NO 35987-91-8


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CAS No.:35987-91-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Furylmethylpenicillin is a semisynthetic penicillin derivative, a key intermediate in the synthesis of advanced β-lactam antibiotics. Its value lies in providing a versatile furan-containing side chain, which is crucial for modifying the antibacterial spectrum and pharmacokinetic properties of final drug compounds. This high-purity intermediate is essential for pharmaceutical R&D laboratories and manufacturers engaged in the development of novel penicillin and cephalosporin-based therapeutics targeting resistant bacterial strains.

Application

  • Pharmaceutical Intermediate: Primary building block for the synthesis of novel β-lactam antibiotics.
  • Antibacterial Research: Used in medicinal chemistry to study structure-activity relationships (SAR) of penicillin derivatives.
  • API Synthesis: Key precursor in the multi-step production of active pharmaceutical ingredients (APIs) with enhanced efficacy.
  • Combinatorial Chemistry: Valuable scaffold for generating libraries of compounds in drug discovery programs.
  • Biochemical Studies: Serves as a tool compound for investigating bacterial resistance mechanisms to β-lactams.

Basic Information

Item Details
Product Name 3-Furylmethylpenicillin
CAS No. 35987-91-8
Molecular Formula C15H18N2O5S
Molecular Weight 338.38 g/mol
Synonyms Penicillin V, 3-Furylmethyl Ester; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 3-Furylmethyl Ester; 3-Furfurylmethyl Penicillin; Phenoxymethylpenicillin 3-Furylmethyl Ester; 6-(Phenoxyacetamido)penicillanic Acid 3-Furylmethyl Ester
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Quality Control

Our 3-Furylmethylpenicillin is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing chromatographic purity, residual solvents, and related substances are provided to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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