Description

Benzoic Acid, 3,4-Bis(2,2,2-Trifluoroethoxy) is a high-value, fluorinated derivative of benzoic acid, distinguished by its two trifluoroethoxy substituents which impart unique physicochemical properties. This compound is critical for applications requiring enhanced lipophilicity, metabolic stability, and electronic characteristics. It serves as a sophisticated building block and intermediate in advanced research and industrial synthesis, particularly within the pharmaceutical and agrochemical sectors. The precise functionalization makes it indispensable for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the trifluoroethoxy groups enhance biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a core component in the synthesis of fluorinated liquid crystals and organic semiconductors for display technologies and electronic devices.
• Polymer Modification: Acts as a monomer or additive to introduce fluorine into polymer chains, improving chemical resistance, thermal stability, and surface properties of high-performance plastics and coatings.
• Organic Synthesis & Catalysis: A versatile building block in organic chemistry for constructing complex molecules; also used as a ligand precursor in metal-catalyzed reactions.
• Advanced Material Research: Employed in R&D for metal-organic frameworks (MOFs), supramolecular chemistry, and other specialty materials requiring tailored aromatic fluorination.

Basic Information

Product Name	Benzoic Acid, 3,4-Bis(2,2,2-Trifluoroethoxy)
CAS No.	35480-54-7
Molecular Formula	C11H8F6O4
Molecular Weight	318.17 g/mol
Synonyms	3,4-Bis(2,2,2-trifluoroethoxy)benzoic Acid; 3,4-Bis(2,2,2-Trifluoroethoxy)benzoic Acid; 3,4-Di(2,2,2-trifluoroethoxy)benzoic Acid; Benzoic acid, 3,4-bis(2,2,2-trifluoroethoxy)-; 35480-54-7; 3,4-Bis(trifluoroethoxy)benzoic Acid; 3,4-Bis(2,2,2-trifluoroethoxy)benzenecarboxylic Acid
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 3,4-Bis(2,2,2-Trifluoroethoxy) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. Due to its organic acid nature and fluorinated structure, it should be handled in a manner that minimizes exposure to moisture and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.