Description

2,6-Bis-(2,2,2-Trifluoro-Ethoxy)-Benzoic Acid is a high-value, fluorinated benzoic acid derivative characterized by its unique trifluoroethoxy substituents, which impart significant chemical stability and specific electronic properties. This compound is critical for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals where fluorine incorporation is desired to modulate bioavailability and metabolic stability. It serves as a sophisticated building block for medicinal chemists and material scientists in pharmaceutical, agrochemical, and advanced material sectors seeking to develop next-generation products with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms contribute to improved lipophilicity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes due to its influence on molecular alignment and electronic properties.
• Polymer Modification: Acts as a monomer or additive for introducing fluorine into polymer backbones, enhancing chemical resistance and thermal stability of specialty plastics and coatings.
• Chemical Research & Development: Employed as a versatile fluorinated building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Complex Ligand Synthesis: Useful for preparing specialized ligands in catalysis and metal-organic frameworks (MOFs) for separation and sensing applications.

Basic Information

Product Name	2,6-Bis-(2,2,2-Trifluoro-Ethoxy)-Benzoic Acid
CAS No.	35480-53-6
Molecular Formula	C13H10F6O4
Molecular Weight	344.21 g/mol
Synonyms	2,6-Bis(2,2,2-trifluoroethoxy)benzoic acid; Benzoic acid, 2,6-bis(2,2,2-trifluoroethoxy)-; 2,6-Di(2,2,2-trifluoroethoxy)benzoic acid; 2,6-Bis(trifluoroethoxy)benzoic acid; 2,6-Bis-(2,2,2-trifluoroethoxy)-benzoesäure (German); Acide 2,6-bis(2,2,2-trifluoroéthoxy)benzoïque (French)
EINECS	Contact for details

Quality Control

Every batch of 2,6-Bis-(2,2,2-Trifluoro-Ethoxy)-Benzoic Acid is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.