Description

3-(2,2,2-Trifluoroethoxy)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block, valued for its unique trifluoroethoxy substituent which imparts significant electronic and steric properties. This compound is essential for advanced research and development in life sciences, enabling the synthesis of novel molecules with tailored biological activity and physicochemical profiles. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, where the trifluoroethoxy group enhances lipophilicity and systemic activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials, improving the thermal stability and electro-optical performance of display components.
• Polymer Modification: Incorporated as a monomer or additive to engineer specialty polymers with enhanced chemical resistance, lower dielectric constants, and improved surface properties.
• Chemical Research & Development: A versatile building block in medicinal and synthetic chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Coordination Chemistry Ligand: The carboxylic acid functionality allows it to act as a ligand for metal complexes used in catalysis and material science.

Basic Information

Product Name	3-(2,2,2-Trifluoroethoxy)Benzoic Acid
CAS No.	35480-48-9
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	3-(2,2,2-Trifluoroethoxy)benzoic acid; Benzoic acid, 3-(2,2,2-trifluoroethoxy)-; m-(Trifluoroethoxy)benzoic Acid; 3-(Trifluoroethoxy)benzoic Acid; 2,2,2-Trifluoroethyl 3-carboxyphenyl ether; 35480-48-9; 3-Carboxytrifluoroethoxyphenyl; 3-TFEOBA
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity fine chemicals. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.