Description

2-(2,2,2-Trifluoroethoxy)Benzoic Acid is a high-value fluorinated aromatic building block, essential for introducing the trifluoroethoxy moiety into complex molecular architectures. This compound is critical for researchers and manufacturers requiring precise chemical modifications to enhance the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily sought after by the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates in active ingredient development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoroethoxy group can improve compound efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronics: Employed in the development of organic semiconductors and electron-transport materials due to its electron-withdrawing properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination strategies and creating novel chemical entities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific fine chemicals and advanced intermediates.

Basic Information

Product Name	2-(2,2,2-Trifluoroethoxy)Benzoic Acid
CAS No.	35480-46-7
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	Benzoic acid, 2-(2,2,2-trifluoroethoxy)-; o-(2,2,2-Trifluoroethoxy)benzoic acid; 2-(Trifluoroethoxy)benzoic acid; 2-(2,2,2-Trifluoroethoxy)benzoic acid; 2-TFEOBA; 35480-46-7; 2-(2,2,2-Trifluoroethoxy)benzoic acid CAS 35480-46-7
EINECS	Contact for details

Quality Control

Our 2-(2,2,2-Trifluoroethoxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.