Description

4-Chloro-2-Fluoro-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen and nitro functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those containing fluorinated and chlorinated aromatic rings.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the nitro and halogen substituents confer specific biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating complex organic molecules used in electronic displays and optoelectronic devices.
• Dyestuff & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments requiring nitro-substituted benzoic acid derivatives.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Nitrobenzoic Acid
CAS No.	35112-05-1
Molecular Formula	C7H3ClFNO4
Molecular Weight	219.55 g/mol
Synonyms	5-Nitro-2-fluoro-4-chlorobenzoic Acid; 2-Fluoro-4-chloro-5-nitrobenzoic Acid; 4-Chloro-2-fluoro-5-nitrobenzoic acid; Benzoic acid, 4-chloro-2-fluoro-5-nitro-; 35112-05-1; 4-Chloro-2-fluoro-5-nitro-benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-5-Nitrobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.