Description

n-Dansyl-L-Threonine Cyclohexylammonium is a high-purity, fluorescently labeled amino acid derivative used as a critical reagent in advanced biochemical research and analytical method development. Its value lies in the dansyl group, a powerful fluorophore that enables sensitive detection and quantification in complex matrices. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors who require precise tools for peptide sequencing, protein analysis, and fluorescence-based assays.

Application

• Fluorescent Labeling Agent: Used for the pre-column or post-column derivatization of amino acids, peptides, and proteins for enhanced detection in chromatographic separations (HPLC, UPLC).
• Biomarker Research: Serves as a standard or reference compound in the development of fluorescence-based assays for studying enzymatic activity, protein-protein interactions, and metabolic pathways.
• Pharmaceutical Analysis: Employed in the quality control of peptide-based drugs and in pharmacokinetic studies to track and quantify biomolecules with high sensitivity.
• Proteomics & Peptide Chemistry: Acts as a building block or tracer in solid-phase peptide synthesis (SPPS) and in mass spectrometry for peptide sequencing and identification.
• Diagnostic Kit Development: Utilized in the formulation of diagnostic reagents and kits that rely on fluorescence detection for clinical and research applications.

Basic Information

Product Name	n-Dansyl-L-Threonine Cyclohexylammonium
CAS No.	35021-16-0
Molecular Formula	C22H35N3O5S
Molecular Weight	453.60 g/mol
Synonyms	L-Threonine, N-[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-, compd. with cyclohexanamine (1:1); Dansyl-L-threonine cyclohexylammonium salt; N-Dansyl-L-threonine cyclohexylamine salt; 5-Dimethylaminonaphthalene-1-sulfonyl-L-threonine cyclohexylammonium salt; DNS-Thr-OH·C6H13N; Fluorescent threonine derivative
EINECS	Contact for details

Quality Control

Our n-Dansyl-L-Threonine Cyclohexylammonium is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for analytical and research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay (HPLC), optical rotation, and impurity profile. We support compliance with relevant industry guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.