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Poly(2'-Deoxyinosinic-2'-Deoxycytidylic Acid) Sodium Salt CAS NO 34607-75-5


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CAS No.:34607-75-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Poly(2'-Deoxyinosinic-2'-Deoxycytidylic Acid) Sodium Salt is a synthetic polynucleotide copolymer, specifically an alternating polymer of deoxyinosinic and deoxycytidylic acids. This compound is of significant value in biochemical and molecular biology research due to its role as a template and substrate. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in nucleic acid studies, enzyme assays, and the development of molecular probes.

Application

  • Molecular Biology Research: Used as a defined template for studying DNA polymerases, reverse transcriptases, and other nucleic acid-modifying enzymes.
  • Biochemical Assays: Serves as a standard or substrate in enzymatic activity tests and kinetic studies.
  • Diagnostic Development: Employed in the research and production of diagnostic assays that require synthetic polynucleotide components.
  • Polymerase Chain Reaction (PCR) Optimization: Can be utilized as a control or non-specific template in PCR protocol development and troubleshooting.
  • Nucleic Acid Hybridization Studies: Acts as a probe or competitor in hybridization experiments due to its specific base sequence.
  • Pharmaceutical R&D: Investigated for potential applications in antisense oligonucleotide research and related therapeutic areas.

Basic Information

Product Name Poly(2'-Deoxyinosinic-2'-Deoxycytidylic Acid) Sodium Salt
CAS No. 34607-75-5
Molecular Formula (C10H12N4O6P • C9H12N3O6P)n • xNa
Molecular Weight Variable (Polymer)
Synonyms Poly(dI-dC) • Poly(deoxyinosinic-deoxycytidylic acid) sodium salt • Poly(dI-dC):Na • Poly(dI-dC) sodium salt • Poly(deoxyinosinic acid-deoxycytidylic acid) • Alternating dI-dC copolymer • Polynucleotide (dI-dC)n • dIdC copolymer
EINECS Contact for details

Quality Control

Our Poly(2'-Deoxyinosinic-2'-Deoxycytidylic Acid) Sodium Salt is produced under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes rigorous analytical testing, including assessment of polymer length, base composition, and sodium content. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and physical properties is provided with every shipment to ensure traceability and meet the stringent requirements of the life science industry.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, desiccate at low temperature. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white fibrous solid or lyophilized powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95% (Polynucleotide content)
Base Ratio (dI:dC) ~1:1 (by UV or HPLC)
Chain Length (Sizing) Specified range available (e.g., 0.5-3 kb pairs)
Solubility Soluble in water, TE buffer
pH (1% Solution) 6.0 - 8.0
Endotoxin < 10 EU/mg (if required)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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