Description

2,3,4,5,6-Pentafluorocinnamic Acid is a high-value fluorinated aromatic building block characterized by its cinnamic acid core with a fully fluorinated phenyl ring. This compound is essential for introducing the unique physicochemical properties of perfluorinated aromatics into advanced molecular architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, leveraging fluorine's ability to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atoms can improve lipophilicity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display technologies, contributing to improved charge transport and thermal stability.
• Polymer & Resin Modification: Incorporated as a monomer or cross-linking agent to produce specialty polymers with enhanced chemical resistance and surface properties.
• Organic Synthesis & Catalysis: Acts as a versatile substrate in cross-coupling reactions (e.g., Heck reaction) and as a ligand precursor in organometallic chemistry.
• Fluorescent Probe & Sensor Development: Utilized in the design of fluorophore cores for chemical sensing and bio-imaging applications due to its electron-withdrawing perfluorophenyl group.

Basic Information

Product Name	2,3,4,5,6-Pentafluorocinnamic Acid
CAS No.	34234-46-3
Molecular Formula	C9H3F5O2
Molecular Weight	238.11 g/mol
Synonyms	(2,3,4,5,6-Pentafluorophenyl)acrylic Acid; Pentafluorocinnamic Acid; Perfluorocinnamic Acid; 3-(Perfluorophenyl)-2-propenoic Acid; 3-(2,3,4,5,6-Pentafluorophenyl)propenoic Acid; α,2,3,4,5,6-Hexafluorocinnamic Acid; Pentafluorocinammic Acid (common misspelling); PFC Acid (abbreviation)
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorocinnamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (HPLC), identity confirmation (IR, NMR), and impurity profiles. Specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.