Description

[2S-(2Alpha,4Beta,5Alpha,6Beta)]-3,3-Dimethyl-7-Oxo-6-(Phenylacetamido)-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid 4-Oxide is a high-purity pharmaceutical intermediate and a key sulfoxide derivative in the penicillin class. This compound is critical for the synthesis and research of advanced β-lactam antibiotics, offering a precise chemical building block for developing new therapeutic agents. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on antimicrobial drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of penicillin and cephalosporin-based antibiotics.
• Active Pharmaceutical Ingredient (API) Research: Used in the development and study of novel β-lactam antibiotic candidates.
• Process Chemistry & Scale-Up: Serves as a standard or starting material for optimizing manufacturing routes for antibiotic APIs.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) and resistance mechanisms of β-lactam drugs.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Fine Chemical Synthesis: A specialized building block for creating complex molecules in medicinal chemistry programs.

Basic Information

Product Name	[2S-(2Alpha,4Beta,5Alpha,6Beta)]-3,3-Dimethyl-7-Oxo-6-(Phenylacetamido)-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid 4-Oxide
CAS No.	34104-15-9
Molecular Formula	C16H18N2O5S
Molecular Weight	350.39 g/mol
Synonyms	Penicillin Sulfoxide; 6-Phenylacetamidopenicillanic Acid Sulfoxide; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-oxide; Ampicillin Sulfoxide Intermediate; Penicillanic Acid Sulfoxide Derivative; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, 4-oxide, (2S,5R,6R)-; 34104-15-9
EINECS	Contact for details

Quality Control

Our [2S-(2Alpha,4Beta,5Alpha,6Beta)]-3,3-Dimethyl-7-Oxo-6-(Phenylacetamido)-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid 4-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.