Description

Mecillinam CAS NO 32887-01-7 is a semisynthetic β-lactam antibiotic belonging to the amidinopenicillin class, specifically active against Gram-negative bacteria. Its primary commercial value lies in its role as a key pharmaceutical intermediate for the synthesis of pivmecillinam, a prodrug used in specific antibacterial therapies. This compound is essential for manufacturers in the pharmaceutical and fine chemical sectors engaged in antibiotic production and advanced research.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of the prodrug antibiotic pivmecillinam hydrochloride.
• Antibacterial Agent Research: Serves as a reference standard and active component in microbiological and pharmacological R&D for studying β-lactam mechanisms.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled production of finished dosage forms for specific antibiotic medications in markets where mecillinam is approved.
• Veterinary Pharmaceutical Synthesis: Potential application in developing antibacterial treatments for veterinary use.
• Biochemical Tool: Utilized in laboratory studies to investigate bacterial cell wall synthesis and penicillin-binding protein (PBP) interactions.

Basic Information

Product Name	Mecillinam
CAS No.	32887-01-7
Molecular Formula	C15H23N3O3S
Molecular Weight	325.43 g/mol
Synonyms	Amdinocillin; Selexid (brand name); FL 1060; 6β-[(Hexahydro-1H-azepin-1-yl)methyleneamino]penicillanic acid; (2S,5R,6R)-6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Amidino penicillin; Mecillinamum
EINECS	251-279-6

Quality Control

Our Mecillinam is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical intermediate applications. Certificates of Analysis (COA) are supplied with each batch, detailing parameters such as assay, related substances, and residual solvents. Quality is assured through HPLC, IR, and titration methods, ensuring compliance with relevant internal and customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.