Description

5-Bromo-3-(10-Methoxy-1,6-Dimethylergolin-8Beta-Ylmethoxycarbonyl)Pyridinium Hydrogen [R-(R*,R*)]-Tartrate is a high-purity, complex organic salt derivative of an ergoline alkaloid, designed for advanced pharmaceutical research and development. This compound is critical for its role as a key synthetic intermediate or reference standard in the development of novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex drug candidates, particularly those with ergot alkaloid backbones.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating receptor binding affinity, enzyme inhibition, and other pharmacological mechanisms of action.
• Process Chemistry Development: Acts as a key intermediate for optimizing scalable and efficient synthetic routes in pilot-scale and commercial API manufacturing.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry projects and the exploration of new chemical entities.

Basic Information

Product Name	5-Bromo-3-(10-Methoxy-1,6-Dimethylergolin-8Beta-Ylmethoxycarbonyl)Pyridinium Hydrogen [R-(R*,R*)]-Tartrate
CAS No.	32222-75-6
Molecular Formula	C₂₈H₃₂BrN₃O₈
Molecular Weight	618.48 g/mol
Synonyms	5-Bromo-3-[(10-methoxy-1,6-dimethyl-8β-ergolinyl)methoxycarbonyl]pyridinium hydrogen (2R,3R)-tartrate; 5-Bromo-3-((10-methoxy-1,6-dimethylergolin-8β-yl)methoxycarbonyl)pyridinium hydrogen tartrate; 5-Bromo-3-(10-methoxy-1,6-dimethyl-8β-ergolinylmethoxycarbonyl)pyridinium bitartrate; 5-Bromo-3-carboxy-1-(10-methoxy-1,6-dimethylergolin-8β-yl)pyridinium tartrate salt; L-702,958 (as tartrate salt); Ergot alkaloid derivative tartrate salt; 5-Br-3-ergolinyl-pyridinium tartrate
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-(10-Methoxy-1,6-Dimethylergolin-8Beta-Ylmethoxycarbonyl)Pyridinium Hydrogen [R-(R*,R*)]-Tartrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing comprehensive test results, including HPLC purity, chiral purity, and residual solvent analysis, are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.