Description

5-Formyl-2'-Deoxyuridylic Acid is a modified nucleoside monophosphate derivative of deoxyuridine, featuring a formyl group at the 5-position of the uracil base. This specific modification makes it a valuable biochemical precursor and research tool for studying nucleic acid metabolism, enzyme mechanisms, and DNA repair pathways. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic reagent synthesis.

Application

• Biochemical Research: As a substrate or inhibitor for enzymes involved in nucleotide metabolism, such as thymidylate synthase.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel antiviral or anticancer nucleoside analogs.
• Diagnostic Development: Used in the preparation of labeled probes or standards for assays detecting DNA damage or specific enzymatic activities.
• Enzyme Mechanism Studies: Employed to investigate the catalytic pathways and binding affinities of DNA-modifying enzymes.
• Reference Standard: Acts as a high-purity analytical standard for quality control in nucleotide-related manufacturing and research.

Basic Information

Product Name	5-Formyl-2'-Deoxyuridylic Acid
CAS No.	31385-28-1
Molecular Formula	C10H13N2O9P
Molecular Weight	336.19 g/mol
Synonyms	5-Formyl-2'-deoxyuridine 5'-monophosphate; 5-FordUMP; 5-Formyldeoxyuridylic Acid; 5-Formyl-dUMP; 5-CHO-dUMP; 2'-Deoxy-5-formyluridylic Acid; (2R,3S,5R)-5-(4-Formyl-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl dihydrogen phosphate
EINECS	Contact for details

Quality Control

Our 5-Formyl-2'-Deoxyuridylic Acid is produced under stringent conditions to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.