Description

Adenosine 5'-P(1)-Triphosphate-P(3)-5'''-Uridine is a specialized dinucleotide compound, also known as Ap3U, formed by the linkage of adenosine triphosphate (ATP) and uridine. This molecule is of significant interest in biochemical research and pharmaceutical development due to its role as a potential substrate or inhibitor for various enzymes involved in nucleotide metabolism and signaling pathways. It is primarily utilized by research institutions, diagnostic manufacturers, and biotechnology companies engaged in enzymology studies, assay development, and high-throughput screening for drug discovery.

Application

• Biochemical Research: Used as a specialized substrate or reference standard in enzymatic assays to study ATP-dependent kinases, ligases, and other nucleotide-binding proteins.
• Pharmaceutical Development: Serves as a key intermediate or tool compound in the discovery and screening of novel therapeutics targeting nucleotide metabolism pathways.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits and reagents for clinical testing and research applications requiring specific nucleotide analogs.
• Enzymology Studies: Employed to investigate enzyme kinetics, mechanism of action, and inhibition profiles of various phosphotransferases.
• Molecular Biology: Potential use in specialized nucleic acid synthesis and labeling techniques.

Basic Information

Product Name	Adenosine 5'-P(1)-Triphosphate-P(3)-5'''-Uridine
CAS No.	30632-06-5
Molecular Formula	C19H25N7O18P3
Molecular Weight	756.36 g/mol
Synonyms	Ap3U; P1-(5'-Adenosyl) P3-(5'-uridyl) triphosphate; Adenosine 5'-(tetrahydrogen triphosphate), 5'-5'''-ester with uridine; Adenyluridyl triphosphate; ATP-Uridine conjugate; 5'-Adenylyl-(5'→5')-uridylyl-(3'→5')-adenosine triphosphate (related isomer); Uridine, 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine 5'-(triphosphate)
EINECS	Contact for details

Quality Control

Our Adenosine 5'-P(1)-Triphosphate-P(3)-5'''-Uridine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and requires desiccant for long-term storage. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.