Description

Diapamide CAS NO 3688-85-5 is a high-purity sulfonamide derivative with significant pharmacological activity. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical agents, particularly diuretics and antihypertensive medications. It is essential for research and development laboratories, fine chemical synthesis, and the production of active pharmaceutical ingredients (APIs) targeting cardiovascular and renal systems.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of diuretic and antihypertensive drugs.
• Research & Development: Utilized in medicinal chemistry for the discovery and optimization of new sulfonamide-based therapeutic candidates.
• Fine Chemical Synthesis: Serves as a versatile reagent in multi-step organic synthesis for creating complex molecular structures.
• API Manufacturing: Incorporated into the production process of bulk active pharmaceutical ingredients under controlled GMP environments.
• Biochemical Research: Used in studies investigating carbonic anhydrase inhibition and related physiological pathways.

Basic Information

Product Name	Diapamide
CAS No.	3688-85-5
Molecular Formula	C11H11ClN2O4S2
Molecular Weight	334.80 g/mol
Synonyms	4-Chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide; 4-Chloro-3-sulfamoyl-N-(2,6-dimethylpiperidino)benzamide; Diapamid; Cl-366; Bay-1521; Benzamide, 4-chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoyl-; 4-Chloro-3-sulfamoylbenzoic acid 2,6-dimethylpiperidide
EINECS	223-008-8

Quality Control

Our Diapamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including a detailed Certificate of Analysis (COA) for each lot, verifying identity, purity, and impurity profiles. Quality is assured through validated methods including HPLC, IR spectroscopy, and residual solvent analysis, meeting the stringent requirements for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.