Description

(S)-Tiopronin is the pharmacologically active S-enantiomer of the thiol compound tiopronin. This high-purity chiral building block is critical for ensuring the efficacy and safety of advanced pharmaceutical formulations. It is primarily required by manufacturers in the pharmaceutical and biotechnology sectors for the development and production of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for therapeutic agents targeting liver conditions, cystinuria, and as a radioprotectant.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiomerically pure APIs.
• Hepatoprotective Agent: Used in formulations for treating liver disorders such as hepatitis and cirrhosis.
• Antiurolithic Therapy: Active ingredient in medications for cystinuria, helping to reduce cystine stone formation.
• Radioprotective Agent: Employed in adjunct therapies to mitigate side effects from radiation exposure.
• Antioxidant Formulations: Utilized in advanced drug delivery systems for its free radical scavenging properties.
• Research & Development: Serves as a standard and building block in biochemical and pharmacological research.

Basic Information

Product Name	(S)-Tiopronin
CAS No.	3625-85-2
Molecular Formula	C5H9NO3S
Molecular Weight	163.19 g/mol
Synonyms	(S)-2-Mercaptopropionylglycine; (S)-α-Mercaptopropionylglycine; (S)-MPG; (S)-Thiola; (S)-Tiopronin; (S)-Acadione; (2S)-2-(2-Sulfanylcarbonylethyl)aminoacetic acid; (S)-N-(2-Mercapto-1-oxopropyl)glycine
EINECS	222-847-8

Quality Control

Our (S)-Tiopronin is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards suitable for pharmaceutical development, with comprehensive analysis including chiral purity, chemical assay, and impurity profiling. Certificates of Analysis (COA) are available upon request, detailing compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% (S-enantiomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.