Description

5-Methyluridine 5'-Monophosphate is a modified nucleoside monophosphate, a key building block in nucleic acid research and development. This compound is critical for studying RNA structure, function, and metabolism, as well as for the synthesis of oligonucleotides with specific properties. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic reagent production.

Application

• Oligonucleotide Synthesis: As a modified monomer for the solid-phase synthesis of research-grade and therapeutic oligonucleotides.
• Biochemical Research: A substrate for enzymatic studies involving RNA polymerases, kinases, and other nucleic acid-modifying enzymes.
• Antiviral & Anticancer Agent Development: Serves as a precursor or analog in the research of nucleoside-based prodrugs and small molecule therapeutics.
• Diagnostic Reagents: Used in the formulation of probes and primers for advanced molecular diagnostic assays.
• RNA Labeling & Tracing: Incorporation into RNA molecules for metabolic tracing and structural studies via spectroscopic methods.

Basic Information

Product Name	5-Methyluridine 5'-Monophosphate
CAS No.	3590-47-4
Molecular Formula	C11H15N2O9P
Molecular Weight	350.22 g/mol
Synonyms	5-Methyluridylic acid; 5-Methyl-UMP; m5UMP; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(phosphonooxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 5-Methyluridine phosphate; 5-Methyluridine 5'-(dihydrogen phosphate); Thymine ribonucleoside 5'-monophosphate
EINECS	Contact for details

Quality Control

Our 5-Methyluridine 5'-Monophosphate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.