Description

Benzbromarone is a potent uricosuric agent primarily used in the research and development of pharmaceuticals targeting hyperuricemia and gout. Its mechanism of action involves the selective inhibition of renal urate reabsorption, promoting its excretion. This compound is of significant interest to pharmaceutical manufacturers and research institutions focused on metabolic disorders and renal function.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of prescription medications for the treatment of chronic gout and hyperuricemia.
• Biochemical Research: Used as a reference standard and tool compound in studies investigating urate transport mechanisms in renal proximal tubules.
• Metabolic Disorder Studies: Applied in preclinical research models to study the pathophysiology and potential treatments for conditions related to purine metabolism.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Drug Discovery & Development: A key intermediate or target molecule in the synthesis and screening of novel uricosuric agents with improved safety profiles.

Basic Information

Item	Details
Product Name	Benzbromarone
CAS No.	3562-84-3
Molecular Formula	C17H12Br2O3
Molecular Weight	424.09 g/mol
Synonyms	2-Ethyl-3-(3,5-dibromo-4-hydroxyphenyl)benzofuran-7-carboxylic acid; 2-Ethyl-3-(4-hydroxy-3,5-dibromobenzoyl)benzofuran; 3-(3,5-Dibromo-4-hydroxyphenyl)-2-ethylbenzofuran-7-carboxylic acid; Desyrel; Minuric; Normurat; Urinorm; Benzobromarone; NSC-113884
EINECS	222-627-7

Quality Control

Our Benzbromarone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by IR and NMR, and tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) compliant with current industry and regulatory expectations for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.