Description

Ethyl (Pentafluorobenzoyl)Acetate is a high-value fluorinated organic building block, specifically an ester derivative of pentafluorobenzoylacetic acid. This compound is prized for its unique reactivity profile, which stems from the electron-deficient pentafluorophenyl ring, making it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the pentafluorophenyl group can improve product efficacy and environmental profile.
• Material Science Research: Serves as a monomer or building block for creating specialty polymers and advanced organic materials with specific electronic or surface properties.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its strong electron-withdrawing character.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research focused on exploring new reactions and methodologies in organofluorine chemistry.

Basic Information

Product Name	Ethyl (Pentafluorobenzoyl)Acetate
CAS No.	3516-87-8
Molecular Formula	C11H7F5O3
Molecular Weight	282.16 g/mol
Synonyms	Ethyl 4,4,4-Trifluoro-3-oxo-3-(pentafluorophenyl)butanoate; Ethyl 3-Oxo-3-(pentafluorophenyl)propanoate; Ethyl Pentafluorobenzoylacetate; 3-Oxo-3-(pentafluorophenyl)propionic Acid Ethyl Ester; Acetic acid, (pentafluorobenzoyl)-, ethyl ester; Ethyl (perfluorobenzoyl)acetate; Pentafluorobenzoylacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our production of Ethyl (Pentafluorobenzoyl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.