Description

6α-[[Amino(3-Chlorophenyl)Acetyl]Amino]Penicillanic Acid is a key semi-synthetic penicillin derivative and a crucial intermediate in the synthesis of advanced β-lactam antibiotics. This compound matters for its role in developing potent antimicrobial agents with targeted activity, addressing the critical need for new therapeutic options in pharmaceutical R&D. It is primarily needed by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of next-generation antibiotics.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel β-lactam antibiotics, including certain penicillins and cephalosporins.
• Antimicrobial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and develop new antibacterial compounds.
• Fine Chemical Synthesis: Serves as a specialized intermediate in multi-step organic syntheses for complex active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	6α-[[Amino(3-Chlorophenyl)Acetyl]Amino]Penicillanic Acid
CAS No.	3495-65-6
Molecular Formula	C16H18ClN3O4S
Molecular Weight	383.85 g/mol
Synonyms	6-[[Amino(3-chlorophenyl)acetyl]amino]penicillanic acid; (2S,5R,6R)-6-[[(2R)-2-Amino-2-(3-chlorophenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-APA derivative; 3-Chloro-D-phenylglycyl-6-APA; Ampicillin intermediate analog; 6-[(Amino(3-chlorophenyl)acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6α-[[Amino(3-Chlorophenyl)Acetyl]Amino]Penicillanic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.