Description

Carbobenzyloxy-o-Benzyl-L-Tyrosine n-Hydroxysuccinimide Ester is a highly reactive, protected amino acid derivative used as a key building block in peptide synthesis. This compound matters for its role in facilitating efficient and selective amide bond formation, enabling the production of complex peptides and proteins with high purity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A critical reagent for the controlled, stepwise addition of protected tyrosine residues to growing peptide chains.
• Solution-Phase Peptide Synthesis: Used in the synthesis of peptide fragments and small peptides in solution, offering flexibility in coupling strategies.
• Bioconjugation: Facilitates the covalent attachment of peptides or tyrosine-containing motifs to other biomolecules, surfaces, or polymers for creating targeted drug delivery systems or diagnostic probes.
• Pharmaceutical Intermediate: Serves as a key intermediate in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in the study of enzyme-substrate interactions, protein structure-function relationships, and signal transduction pathways.
• Production of Custom Peptides: Essential for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides for clients.

Basic Information

Product Name	Carbobenzyloxy-o-Benzyl-L-Tyrosine n-Hydroxysuccinimide Ester
CAS No.	3480-76-0
Molecular Formula	C26H24N2O7
Molecular Weight	476.48 g/mol
Synonyms	Z-Tyr(Bzl)-OSu; Cbz-Tyr(Bzl)-OSu; N-Carbobenzyloxy-O-benzyl-L-tyrosine N-hydroxysuccinimide ester; Nα-Cbz-O-benzyl-L-tyrosine N-hydroxysuccinimide ester; NSC 334381; (2,5-Dioxopyrrolidin-1-yl) (2S)-3-(4-benzyloxyphenyl)-2-[(phenylmethoxy)carbonylamino]propanoate; Z-O-Bzl-L-Tyr-OSu; CBZ-O-Benzyl-L-tyrosine N-hydroxysuccinimide ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as purity, identity, and impurity profiles. We adhere to stringent in-process controls to guarantee batch-to-batch consistency suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.