Description

6α-[(2-Amino-1-Oxohexyl)Amino]Penicillanic Acid is a key semi-synthetic penicillin derivative and a crucial intermediate in the synthesis of advanced β-lactam antibiotics. Its primary value lies in enabling the production of broad-spectrum antibiotics with enhanced stability and efficacy against resistant bacterial strains. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing and producing next-generation antibacterial agents, including certain penicillins and cephalosporins.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced β-lactam antibiotics, including specific semi-synthetic penicillins.
• Antibiotic Research & Development: Used in medicinal chemistry for creating novel antibiotic candidates with improved pharmacological profiles.
• Bulk Drug Substance Manufacturing: Serves as a key precursor in the commercial-scale production of active pharmaceutical ingredients (APIs) for antibacterial medications.
• Biochemical Studies: Employed in research to study the structure-activity relationships (SAR) of penicillin derivatives and their interaction with bacterial enzymes.

Basic Information

Product Name	6α-[(2-Amino-1-Oxohexyl)Amino]Penicillanic Acid
CAS No.	3381-65-5
Molecular Formula	C14H23N3O4S
Molecular Weight	329.42 g/mol
Synonyms	6-[(2-Amino-1-oxohexyl)amino]penicillanic acid; 6-APA derivative; 6-(2-Aminocaproamido)penicillanic acid; Ampicillin intermediate; D-(-)-α-Aminobenzylpenicillin precursor; (2S,5R,6R)-6-[(2-Amino-1-oxohexyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6α-[(2-Amino-1-Oxohexyl)Amino]Penicillanic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.