Description

8-Hydroxypenillic Acid is a specialized organic compound belonging to the penillic acid class, a key structural motif in β-lactam chemistry. This compound is valued for its role as a versatile synthetic intermediate and a crucial reference standard in pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis and analysis of advanced molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel β-lactam derivatives and other complex active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used as a high-purity standard in HPLC, LC-MS, and NMR for the identification, assay, and impurity profiling of related pharmaceutical compounds.
• Biochemical Research: Employed in studies investigating enzyme inhibition, particularly those related to bacterial cell wall synthesis and β-lactamase activity.
• Fine Chemical Synthesis: Acts as a precursor for the development of specialized ligands, catalysts, and other high-value organic compounds in research settings.

Basic Information

Product Name	8-Hydroxypenillic Acid
CAS No.	3053-85-8
Molecular Formula	C8H12N2O4S
Molecular Weight	232.26 g/mol
Synonyms	8-Hydroxypenillic Acid; (2R,5R)-5,5-Dimethyl-2-[(2-oxo-2-[(sulfanylmethyl)amino]acetyl)amino]-4-oxo-1,3-thiazolidine-3-carboxylic Acid; Penillic Acid, 8-hydroxy-; 3-Carboxy-5,5-dimethyl-2-[(2-mercaptoacetamido)acetamido]-4-thiazolidinecarboxylic Acid; 8-HPA
EINECS	221-281-5

Quality Control

Our 8-Hydroxypenillic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.