Description

2-Fluoro-4-Methoxybenzoic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the synergistic reactivity of the fluorine substituent and the methoxy group, enabling precise molecular modifications. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated benzoic acid scaffold for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic chemicals for display and lighting technologies.
• Organic Synthesis & Catalysis: Employed in coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in catalytic systems due to its electron-withdrawing and directing effects.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.
• Fine Chemical Production: Used in the manufacture of dyes, pigments, and other specialty fluorinated compounds.

Basic Information

Product Name	2-Fluoro-4-Methoxybenzoic Acid
CAS No.	394-42-3
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	4-Methoxy-2-fluorobenzoic Acid; 2-Fluoro-4-methoxybenzoic acid; 2-Fluoro-p-anisic Acid; 4-Methoxy-2-fluorobenzoic Acid; Benzoic acid, 2-fluoro-4-methoxy-; 2-Fluoro-4-methoxy-benzoic acid; 2-Fluoro-4-methoxybenzoicacid
EINECS	206-902-5

Quality Control

Our 2-Fluoro-4-Methoxybenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.