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Methyl 2-Fluorobenzoate CAS NO 394-35-4


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CAS No.:394-35-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2-Fluorobenzoate is a versatile fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of the fluorine atom and the methyl ester group, which are pivotal for modifying the physicochemical properties of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity, reliable chemical intermediates for complex synthesis.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom improves biological activity and environmental persistence.
  • Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
  • Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and ester hydrolysis/transformation reactions to create more complex fluorinated molecules.
  • Flavor & Fragrance Intermediate: Utilized in the research and development of novel aromatic compounds for specialty chemical applications.

Basic Information

Product Name Methyl 2-Fluorobenzoate
CAS No. 394-35-4
Molecular Formula C8H7FO2
Molecular Weight 154.14 g/mol
Synonyms 2-Fluorobenzoic Acid Methyl Ester; Methyl o-Fluorobenzoate; o-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 2-fluoro-, methyl ester; Methyl 2-fluorobenzenecarboxylate; 2-Fluoromethylbenzoate; Methyl 2-fluorophenylcarboxylate
EINECS 206-902-9

Quality Control

Our Methyl 2-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Refractive Index (n20D) 1.5050 - 1.5090
Density (20°C) 1.18 - 1.22 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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